Jibing Chen, Jialiang Li, Lihua He et al.
[Abstract]
AIM: To investigate the therapeutic effffect of radical treatment and palliative treatment in stage Ⅳ pancreatic cancer patients.
METHODS: 81 patients were enrolled in the study. Radical treatment was performed on 51 patients, while 30 patients were put under palliative treatment. The procedural safety and interval survival for stage Ⅳ pancreatic cancer (IS-Ⅳ) was assessed by almost 2.5 years of follow-ups. The IS-Ⅳ of patients under the two kinds of treatment, and the effffects of treatment timing and frequency on IS-Ⅳ, were compared.
RESULTS: The IS-Ⅳ of patients who received radical treatment was significantly longer than those who received palliative treatment (P < 0.001). The IS-Ⅳ of patients who received delayed radical or palliative treatment was longer than those who received accordingly timely treatment (P = 0.0034 and 0.0415, respectively). Multiple treatments can play an important role in improving the IS-Ⅳ of patients who received radical treatment (P = 0.0389), but not for those who received palliative treatment (P = 0.99).
CONCLUSION: The effffect of radical treatment was significantly more obvious than that of palliative treatment, and multiple radical treatments may contribute more to patients than a single radical treatment.
[Key words] Cryosurgery; Stage Ⅳ pancreatic cancer; Iodine-125 seed
12Radical treatment of stage Ⅳ pancreatic.pdf