[Abstract] To the Editor: Recurrent breast cancer with distant metastases is tradtionally considered a severe and incurable disease (1–3). In contrast, curative treatment is generally attempted for local recurrence (4). The 5-year overall survival (OS) after an isolated chest wall recurrence is 68% and that after an intra-breast recurrence is 81% (5). Conventional therapies can easily be implemented synchronously with cryoablation with fewer side effects when used in the treatment of malignant breast tumors, primarily, early-stage tumors (6). For the effective prevention of local recurrence and metastases of breast cancer, many immunologic methods have been studied (7). These methods can improve physical and immune function in patients, without causing any obvious side effects and are sustainable in the long term.
14 recurrent breast cancr with metastasis.pdf